Basics of Human Physiology- Digestion

Sol –

  • Insulin is a hormone produced by the pancreas that helps regulate blood sugar (glucose) levels
  • It allows cells to absorb glucose from the bloodstream to use it for energy or store it as glycogen in the liver and muscles. 
  • It prevents high blood sugar and plays a vital role in carbohydrate metabolism.
  • A deficiency or improper functioning of insulin leads to diabetes mellitus, a condition where blood sugar remains abnormally high.

The pancreas is classified as a mixed gland because it has both endocrine and exocrine functions.

Exocrine Function

Endocrine Function

  • Majority of the pancreas; 
  • Secretes digestive enzymes and bicarbonate ions into the small intestine.
  • These enzymes aid in the digestion of carbohydrates, proteins, and fats in the food we consume.
  • contains clusters of cells called islets of Langerhans, composed of different types of hormone-secreting cells.  → secrete hormones directly into the bloodstream to regulate blood sugar levels.
  • Lipase ⇒ Fat → fatty acid + Glycerol 
  • Amylase ⇒ Starch → maltose → Glucose + Glucose
  • Proteases (including trypsin, chymotrypsin, and carboxypeptidase): Break down proteins into smaller peptides and amino acids.
  • Ribonuclease and Deoxyribonuclease: Digest RNA and DNA respectively, breaking them down into nucleotides.
  • Alpha cells (secrete glucagon): Stimulate the liver to release stored glucose into the bloodstream, raising blood sugar levels during fasting or between meals.
  • Beta cells (secrete insulin): Promote the uptake of glucose from the bloodstream into cells, lowering blood sugar levels. 
  • Gamma cells: somatostatin → growth hormone and control secretion of glucose and insulin

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